Soledad Berríos, M.Sc. Professor Director of the Human Genetics Program, ICBM Faculty of Medicine, University of Chile sberrios@med.uchile.cl

Lines of Research

• Structure of the nucleus and functioning of meiosis in spermatocytes that hare heterozygous for Robertsonian changes in chromosomes
• Modifications in nuclear architecture in somatic and meiotic cells from organisms who carry Robertsonian chromosomal changes
• Fertility in inter-specific hybrids: role of proteins involved in synapsis and recombination.

Selected Publications

• Page J, de la Fuente R, Manterola M, Parra MT, Viera A, Berríos S, Fernández-Donoso R, Rufas JS. Inactivation or non-reactivation: what accounts better for the silence of sex chromosomes during mammalian male meiosis? Chromosoma. 2012 Feb 26. ISI: 4.196
• Vasco C, Manterola M, Page J, Zuccotti M, de la FuenteR,RediCA, Fernández-DonosoR, GaragnaS. The frequency of heterologous synapsis increases with aging in Robertsonian heterozygous male mice. Chromosome Res (vol 19) December 2011 (in press). ISI 3.130
• Berrios S, Manterola M, Prieto Z, López-Fenner J, Page J, Fernández-Donoso R (2010) Model of chromosome associations in Mus domesticus spermatocytes. Biol Res 43 (3): 275-285; ISI: 0.849
• Fernández-Donoso R, Berríos S, Rufas JS, Page J. Chapter 10: Marsupial Sex Chromosome Behaviour During Male Meiosis pp 187 – 206, in the book “Marsupial Genetics and Genomics”. Springer. Feakin JE, Waters PD & Marshall Graves JA Eds.
• Manterola, M., Page, J., Vasco, C., Berríos, S., Parra, M. T., Viera, A., Rufas JS., Zuccoti M., Garagna S., Fernández Donoso R. A high incidence of meiotic silencing of unsynapsed chromatin is not associated with substantial pachytene loss in heterozygous male mice carrying multiple simple robertsonian translocations. PLoS Genetics 2009, 5(8) ISI :  8.883
• Page J, De la Fuente R, Parra MT, Viera A, Calvente A, Gómez R,  Suja JA, Berríos S, Manterola M, Fernández-Donoso R and Sánchez-Rufas J.   Sex chromosome inactivation during marsupial meiosis and spermiogenesis.  16th International Chromosome Conference ICC- 2007 25-29 August 2007 Amsterdam,  The Netherlands.  Chromosome Research.  2007; 15, 86-87.   ISI: 3.405
• Page J, Viera A, Parra MT, De la Fuente R, Suja JA, Prieto I, Barbero JL, Sánchez-Rufas J,  Berríos S and Fernández-Donoso R. Involvement of synaptonemal complex proteins in sex chromosome segregation during marsupial meiosis PLoS  Genetics  2006;  Vol.2 Nº 8  Pág 1-14.     ISI : 8.883
• Page J, De la Fuente R, Viera A, Parra MT,  Suja Á, Sánchez-Rufas J, Berríos S and Fernández-Donoso R.  Sex Chromosomes, sinapsis and cohesins: a complex affair Chromosoma (Berl). 2006; Vol.115: Pág 250-259.   ISI: 5.111